Autoimmune Diseases: An Overview

Autoimmune Diseases: An Overview

Autoimmune diseases affect millions of people globally and are increasingly recognised in Australia as a significant contributor to chronic health issues. These conditions occur when the immune system designed to protect the body from harmful invaders starts attacking healthy tissue by mistake.

This guide provides a clear overview of autoimmune diseases, including what causes them, common symptoms and how early diagnosis and tailored treatment can help manage the condition and improve quality of life.

What You will Learn in This Article

  • What are autoimmune diseases?
  • Common autoimmune conditions in Australia
  • Causes and risk factors
  • Signs and symptoms to watch for
  • Diagnosis and treatment pathways
  • Long-term management strategies

What Are Autoimmune Diseases?

Autoimmune diseases develop when the immune system malfunctions and begins attacking the body’s own tissues and organs. Instead of identifying threats such as viruses or bacteria, the immune system wrongly targets healthy cells.

These attacks can cause inflammation, pain, fatigue and damage to the affected body systems. Autoimmune diseases vary widely in their presentation some affect a single organ, while others impact multiple systems. According to Healthdirect Australia, there are over 80 recognised autoimmune diseases.

These conditions are typically chronic and may require long-term care from general practitioners and specialists.

Common Autoimmune Conditions in Australia

The following autoimmune diseases are among the most commonly diagnosed across general practice and specialist settings in Australia:

  • Rheumatoid Arthritis (RA): An inflammatory disorder that targets the joints, causing pain, stiffness and swelling.
  • Coeliac Disease: An autoimmune reaction to gluten, damaging the small intestine and causing digestive symptoms and nutrient deficiencies.
  • Type 1 Diabetes: The immune system destroys insulin-producing cells in the pancreas, affecting blood sugar regulation.
  • Hashimoto’s Thyroiditis: Leads to an underactive thyroid, resulting in fatigue, weight gain and cold sensitivity.
  • Graves’ Disease: Causes an overactive thyroid, leading to symptoms like weight loss, anxiety and heat intolerance.
  • Systemic Lupus Erythematosus (Lupus): Affects multiple organs, including skin, kidneys and joints.
  • Multiple Sclerosis (MS): Damages the protective covering of nerves, affecting coordination and muscle control.
  • Psoriasis and Psoriatic Arthritis: Cause red, scaly skin and joint inflammation.

Recognising these diseases early can reduce the risk of long-term complications and support better health outcomes.

Causes and Risk Factors

The exact cause of autoimmune diseases remains unclear, but research shows a mix of genetic, environmental and lifestyle factors may contribute.

Some of the known risk factors include:

  • Family history of autoimmune disease
  • Female gender women are more likely to develop autoimmune conditions
  • Viral or bacterial infections that may trigger immune dysfunction
  • Environmental exposures such as toxins or pollutants
  • Hormonal changes, especially during puberty, pregnancy or menopause
  • Chronic stress, which can weaken immune regulation

Understanding your risk profile is the first step toward early detection and prevention.

Symptoms of Autoimmune Diseases

Autoimmune conditions often cause generalised symptoms that may be mistaken for other illnesses. If symptoms persist and do not respond to usual treatments, it is important to consider an autoimmune cause.

Common symptoms include:

  • Fatigue that does not improve with rest
  • Ongoing joint or muscle pain
  • Skin rashes or changes in pigmentation
  • Digestive issues like bloating, diarrhoea or nausea
  • Brain fog or difficulty concentrating
  • Unexplained weight changes
  • Increased sensitivity to temperature
  • Recurring fevers or swollen glands

Symptoms can vary depending on the organ or system affected and they may come and go in unpredictable “flare-ups.”

Diagnosing Autoimmune Conditions

Diagnosing autoimmune diseases typically involves a combination of clinical evaluation and diagnostic testing. A general practitioner will begin by reviewing your symptoms, personal history and any family history of chronic illness.

Depending on the suspected condition, the diagnostic process may include:

  • Blood tests for inflammatory markers and auto antibodies (e.g. ANA, rheumatoid factor)
  • Thyroid function tests for hormone imbalances
  • Blood glucose testing for diabetes screening
  • Coeliac serology for gluten sensitivity
  • Specialist referrals, including rheumatology, endocrinology or neurology as needed

Diagnosis can take time, especially when symptoms overlap with other conditions. Patience and regular follow-up with a trusted GP are essential.

Managing Autoimmune Diseases

Although autoimmune diseases cannot be cured, many are manageable with the right treatment strategy. The goal of treatment is to reduce inflammation, minimise flare-ups and support long-term wellbeing.

Management options include:

  • Medications – including anti-inflammatory drugs, corticosteroids, immunosuppressants or biologics
  • Dietary changes – especially for conditions like coeliac disease or inflammatory bowel disease
  • Physical activity – to maintain mobility and reduce stiffness or fatigue
  • Mental health support – as chronic illness can affect emotional wellbeing
  • Allied health services – including physiotherapy, psychology and dietetics
  • Regular monitoring – through blood tests and ongoing consultations

With consistent care, many people with autoimmune diseases go on to lead full and active lives.

Conclusion

Autoimmune diseases are often misunderstood, but with early diagnosis, personalised treatment and ongoing support, patients can manage symptoms and prevent complications. Paying attention to early signs, staying informed and building a long-term relationship with a healthcare provider are key steps toward improved health and quality of life.

About Berkeley Medical Centre

Berkeley Medical Centre, located in Kenmore QLD, provides comprehensive care for individuals living with autoimmune diseases. Our experienced GPs and in-house allied health team offer tailored support for diagnosis, treatment and ongoing management of chronic conditions. Whether you are newly diagnosed or seeking better symptom control, our team delivers evidence-based, compassionate care to help you live well with autoimmune disease.